@sidenavwidth: 250px;._bg,._staticimg{background-size:cover;height:100%}#_toggle-nav,#_vimeodisclaimer,#_youtubedisclaimer,.Centered,._carousel_counter,._carousel_dots,._chart .bars .bar,._x-axis span,._x-axis-grouping,.linedots div.label-above,.linedots div.label-below{text-align:center}@font-face{font-family:Graphik;src:url(/fonts/Graphik-Regular-Web.woff2) format("woff2"),url(/fonts/Graphik-Regular-Web.woff) format("woff")}@font-face{font-family:Graphik;font-weight:500;src:url(/fonts/Graphik-Medium-Web.woff2) format("woff2"),url(/fonts/Graphik-Medium-Web.woff) format("woff")}@font-face{font-family:Graphik;font-weight:600;src:url(/fonts/Graphik-Bold-Web.woff2) format("woff2"),url(/fonts/Graphik-Bold-Web.woff) format("woff")}body{margin:0}._grid{width:100%;display:grid;display:-ms-grid;grid-template-columns:repeat(24,1fr);-ms-grid-columns:1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr 1fr}._block,._block-content{height:100%;box-sizing:border-box}._grid-polyfill ._grid{position:relative}._grid-polyfill ._block{position:absolute}._section,.wrap{box-sizing:border-box;margin:0 auto}.wrap:after{content:'';display:table;clear:both}._block ._bg picture,picture[data-imageid]{display:block;width:100%}._block,._block-content,._section,._section-container{position:relative}.wrap{padding:0 2rem;clear:both}._blocklink{position:absolute;top:0;left:0;width:100%;height:100%;z-index:1}._bg{position:absolute;top:0;left:0;width:100%;overflow:hidden}._block ._bg{padding:inherit;box-sizing:border-box}._block ._bg picture{height:100%;overflow:hidden}._staticimg{width:100%}._bg._middle ._staticimg{background-position-y:50%}._bg._top ._staticimg{background-position-y:0}._bg._bottom ._staticimg{background-position-y:100%}._bg._center ._staticimg{background-position-x:50%}._bg._left ._staticimg{background-position-x:0}._bg._right ._staticimg{background-position-x:100%}._bg img{width:100%;height:100%;object-fit:cover;position:absolute;left:0;top:0}._bg._top._left{background-position:0 0}._bg._top._left img{object-position:0 0}._bg._top._center{background-position:50% 0}._bg._top._center img{object-position:50% 0}._bg._top._right{background-position:100% 0}._bg._top._right img{object-position:100% 0}._bg._middle._left{background-position:0 50%}._bg._middle._left img{object-position:0 50%}._bg._middle._center{background-position:50% 50%}._bg._middle._center img{object-position:50% 50%}._bg._middle._right{background-position:100% 50%}._bg._middle._right img{object-position:100% 50%}._bg._bottom._left{background-position:0 100%}._bg._bottom._left img{object-position:0 100%}._bg._bottom._center img,._section-container.bg-align-top ._bg picture img{object-position:50% 100%}._bg._bottom._center{background-position:50% 100%}._bg._bottom._right{background-position:100% 100%}._bg._bottom._right img{object-position:100% 100%}._bg._vimeo{display:flex;align-items:center;justify-content:center}._bg._vimeo>div{flex:1}._bg._vimeo._bottom{align-items:flex-end}._bg._vimeo._top{align-items:flex-start}._bg._vimeo._left{justify-content:flex-start}._bg._vimeo._right{justify-content:flex-end}._block-content picture>img,p>a>img,p>img{display:inline-block;max-width:100%;height:auto}._block-content picture>img.Centered,p>a>img.Centered,p>img.Centered{display:block;margin:0 auto}.parallax-mirror .parallax-slider{height:100%}.parallax-mirror .parallax-slider img{display:block;min-width:100%;min-height:100%}.parallax-mirror .parallax-slider img.highdensity{position:absolute;top:0;bottom:0}._hasbg ._block-content,._hasbg ._section,div._section-container._hasbg{background:0 0}._bgvideo video{position:absolute;object-fit:cover;width:100%;height:100%}._bg._top._left video{object-position:top left}._bg._top._center video{object-position:top center}._bg._top._right video{object-position:top right}._bg._middle._left video{object-position:middle left}._bg._middle._right video{object-position:middle right}._bg._bottom._left video{object-position:bottom left}._bg._bottom._center video{object-position:bottom center}._bg._bottom._right video{object-position:bottom right}._imagemap{position:relative}._imagemap svg{position:absolute;top:0;left:0;width:100%;height:100%}._imagemap picture>img{display:block}sub,sup{line-height:0;position:relative;vertical-align:baseline}sup{top:-.5em;font-size:75%}sub{bottom:-.25em}@media (max-width:375px){body.live ._hidesp{display:none}}@media (max-width:667px) and (min-width:376px){body.live ._hidesp-l{display:none}}@media (max-width:768px) and (min-width:668px){body.live ._hideta{display:none}}@media (max-width:1024px) and (min-width:769px){body.live ._hideta-l{display:none}}@media (max-width:1366px) and (min-width:1025px){body.live ._hidedt{display:none}}@media (min-width:1366px){body.live ._hidews{display:none}}body.live div[data-showforvisitors]{display:none}._visuallyhidden{clip:rect(0 0 0 0);clip-path:inset(50%);height:1px;overflow:hidden;position:absolute;white-space:nowrap;width:1px}._accordion-heading button{-webkit-appearance:none;border:0;background:0;font-size:inherit;font-family:inherit;font-weight:inherit;padding:0;margin:0;display:block;width:100%;text-align:inherit;line-height:inherit}.js ._accordion{height:0;overflow:hidden;transition:height .3s}._grid._tabpanel[hidden]{display:none}._carousel{display:block;width:100%;overflow:hidden;position:relative}._carousel ._section-container{min-height:400px}._carousel_slides>div{top:0;width:100%;position:relative;display:inline-block;vertical-align:top}._carousel_frame{position:relative;overflow:hidden;line-height:0;white-space:nowrap}._carousel_frame ._block{line-height:2rem;white-space:normal}._carousel_dots{position:absolute;bottom:0;width:100%}._carousel_dots button{background:0;border:1px solid #000;margin-left:.5rem;margin-right:.5rem;width:1rem;height:1rem;border-radius:50%;padding:0}._carousel_dots button span{position:absolute;left:-100vw}._carousel_dots button.selected{background-color:#000}._carousel_dots button::after,._carousel_dots button::before{display:none}._carousel_prevnext{position:absolute;top:50%;left:50%;transform:translate(-50%,-50%);width:100%}._carousel_next,._carousel_prev{position:absolute!important}._carousel_prev{left:0}._carousel_next{right:0}#_vimeodisclaimer,#_youtubedisclaimer{position:absolute;top:0;height:100%;left:0;width:100%;background-color:rgba(255,255,255,.9);box-sizing:border-box;padding:1rem;margin:0;border:2px solid #000;display:flex;align-items:center;justify-content:center}[data-align-h=center] ._block-content,[data-align-h=right] ._block-content{flex-direction:column;display:flex}#_vimeodisclaimer p,#_youtubedisclaimer p{max-width:650px}#_vimeodisclaimer button,#_youtubedisclaimer button{margin-top:2rem}._carousel_counter{position:absolute;bottom:7%;width:100%}[data-align-h=center] ._block-content>*{margin:0 auto}[data-align-h=left] ._block-content>*{margin:0}[data-align-h=right] ._block-content>*{margin:0 0 0 auto}[data-align-v=middle] ._block-content{display:flex;flex-direction:column;justify-content:center}[data-align-v=bottom] ._block-content{display:flex;flex-direction:column;justify-content:flex-end}[data-align-v=bottom] ._block-content picture>img{display:block}[data-align-v=pushbottom] ._block-content{display:flex;flex-direction:column}[data-align-v=pushbottom] ._block-content>:last-child{margin-top:auto}[data-align-v=middle]:not([data-align-h]) ._block-content>*,[data-align-v=bottom]:not([data-align-h]) ._block-content>*,[data-align-v=pushbottom]:not([data-align-h]) ._block-content>*{width:100%}._section-container ._section ._block._blockcollapse,._section-container ._section ._block._blockcollapse ._block-content{padding-bottom:0}._section-container ._section ._block._blockcollapse+._block,._section-container ._section ._block._blockcollapse+._block ._block-content{padding-top:0}._block-content .breadcrumb ol,._block-content .breadcrumb ul{list-style:none;margin:0;padding:0}._block-content .breadcrumb ol li,._block-content .breadcrumb ul li{padding:0;display:inline}#_cookiebanner-opt-in-out.hidden,._cookiebanner-opt-in-out--settings:not(.visible){display:none}._cookiebanner-opt-in-out--inner{position:relative}._cookiebanner-opt-in-out--error-list li{color:red}#disclaimer1 label>span{display:block}#disclaimer1 button,.disclaimerError{display:none}._skiplink{display:block;position:absolute;top:3rem;left:calc(50vw - 100px);z-index:1000;background:#fff;padding:1rem;transform:translateY(-1000vh)}._skiplink:focus{transform:none}form .textfield.waasvalidate{display:none}._form-page{grid-template-columns:repeat(12,1fr)}._form-page:not([hidden]){display:grid}._form-page>h2,._form-page>h3,._form-page>h4{grid-area:1/1/2/13;margin:0;max-width:none}._form-page .textfield>span{display:block}._form-page ._dropdown{position:relative}._form-page ._options{position:absolute;top:100%;left:0;width:100%;display:none;overflow:auto;max-height:25rem}._form-page ._dropdown.visible ._options,._form-page ._options span{display:block}main ._forcedform{display:none;opacity:0;transition:opacity .3s;position:fixed;top:0;left:0;width:100%;height:100%;z-index:12;background-color:rgba(0,0,0,.3);align-items:center}main ._forcedform ._section{width:100%;background-color:#fff}main ._forcedform._visible{display:flex}main ._forcedform._visibleOpen{opacity:1}#_toggle-nav{z-index:3;-webkit-appearance:none;border:0;padding:0;width:60px;height:60px}#_toggle-nav span span{position:absolute;bottom:0;width:100%}#_toggle-nav .show{display:block}#_toggle-nav .hide{display:none}#_toggle-nav::after,#_toggle-nav>span::after,#_toggle-nav>span::before{content:'';background-color:currentColor;position:absolute;height:2px;width:40px;left:10px;transition:all .3s}#_toggle-nav>span{display:block}#_toggle-nav>span::before{top:13px}#_toggle-nav>span::after{top:27px}#_toggle-nav::after,._menutransition #_toggle-nav>span::after,._menutransition #_toggle-nav>span::before{top:20px}._menutransition #_toggle-nav .show{display:none}._mainnav ._toggle svg,._menutransition #_toggle-nav .hide{display:block}._menutransition #_toggle-nav::after{opacity:0}._menutransition #_toggle-nav>span::before{transform:rotate(45deg)}._menutransition #_toggle-nav>span::after{transform:rotate(-45deg)}._mainnav ._toggle{margin:0;padding:0;border:0}._mainnav ._toggle .hide{display:none}._mainnav ._toggle .show,._mainnav .children-visible>._toggle .hide{display:block}._mainnav .children-visible>._toggle .show{display:none}._ribbon{position:absolute;left:0;width:100%;top:100%;box-sizing:border-box;transition:height .3s ease-in-out}._ribbon ul{display:flex;list-style:none}._pagecontent,._pagelist .item{display:grid;display:-ms-grid}._pagelist-filter ._tabs a{display:inline-block;padding:0 1rem}._pagelist-grid{display:grid;grid-gap:2rem;grid-template-columns:repeat(auto-fill,minmax(250px,1fr));grid-auto-rows:2rem;opacity:0}._pagelist-grid h2{grid-column:1/-1}._pagelist-grid.loaded{opacity:1}._chart .hoverlabel .bar span,.linedots div.hoverlabel>span{opacity:0}.ie ._pagelist-grid{display:flex;flex-wrap:wrap;width:calc(100% + 2rem);max-width:none;margin-left:-1rem}.ie ._pagelist-grid .item{width:calc(33.33% - 2rem);margin:1rem}._instantsearch{display:none;position:absolute;top:100%}._subscribe ._result,._subscribe .textfield.waasvalidate,._subscribe._success ._fields{display:none}._chart,._subscribe._fail ._fail,._subscribe._success ._success{display:block}._chart{margin:0;position:relative}._chart .combinedlabel{display:none;position:absolute;white-space:nowrap;pointer-events:none;background:rgba(255,255,255,.9);box-shadow:0 2px 4px rgba(0,0,0,.18);padding:1rem;left:50%;transform:translateX(-50%);margin-bottom:1rem}._chart .combinedlabel ._lbl{padding-left:1rem;position:relative}._chart .combinedlabel ._lbl::after{content:': '}._chart .combinedlabel ._lbl::before,._chart-area:after,._pie-connect:after,._x-axis-grouping span::before,.legend .symbol.line:before,body.live.transparent-header:not(.meganav-open):before{content:''}._chart .combinedlabel ._lbl::before{position:absolute;width:8px;height:8px;left:0;top:.5rem;border-radius:50%}._chart .combinedlabels{z-index:3;display:flex}._chart .combinedlabels>div{flex:1;position:relative}._chart .combinedlabels>div:focus,._chart .combinedlabels>div:hover{background-color:rgba(255,255,255,.2)}._chart .combinedlabels>div:focus .combinedlabel,._chart .combinedlabels>div:hover .combinedlabel{display:block}._chart .bars{z-index:1;display:flex}._chart .bars div{display:flex;flex:1}._chart .bars .bar{position:relative;margin:0 auto;min-width:1px;display:block}._chart .bars .bar span{white-space:nowrap;pointer-events:none}._chart .bars .stackedbar{position:relative}._chart .bars .stackedbar .bar{position:absolute;left:50%;transform:translateX(-50%);width:100%}._chart .nolabel span{display:none}._chart .hoverlabel:hover .bar span{opacity:1}._chart .label-above .bar>span{display:block;transform:translate(0,-100%);position:relative;z-index:1}._chart .chartSymbol,._chart .label-center .bar>span{position:absolute;top:50%;transform:translate(-50%,-50%)}._chart .label-center .bar>span{z-index:1}._chart .chartSymbol{left:50%;width:10px}._chart polygon{fill-opacity:.75}._chart._pie ._chart-area:after{padding-bottom:100%}._chart-title{padding-bottom:1em}._chart-container{display:grid;display:-ms-grid;grid:auto 1fr auto/auto 1fr auto;-ms-grid-columns:auto 1fr auto;-ms-grid-rows:auto 1fr auto;justify-content:stretch}._y-axis{display:flex;flex-direction:column}._y-axis.left{grid-row:2;grid-column:1;-ms-grid-row:2;-ms-grid-column:1;text-align:right}._y-axis.left.top{grid-row:1;-ms-grid-row:1;min-height:2rem}._y-axis.left.bottom{grid-row:3;-ms-grid-row:3}._y-axis.right{grid-row:2;grid-column:3;-ms-grid-row:2;-ms-grid-column:3;text-align:left}._y-axis.right.top{grid-row:1;-ms-grid-row:1;min-height:2rem}._y-axis.right.bottom{grid-row:3;-ms-grid-row:3}._y-axis span{transform:translateY(-1rem);flex:1}._chart-area{position:relative;box-sizing:border-box;grid-row:2;grid-column:2;-ms-grid-row:2;-ms-grid-column:2}._chart-area:after{pointer-events:none;display:block;width:100%}._chart-area>div,._chart-area>svg{position:absolute;width:100%;left:0;top:0;bottom:1px}._chart-area>svg{pointer-events:none;z-index:1}._chart-area line{stroke-linecap:round}.linedots div{position:absolute;z-index:2;width:20px;height:20px;margin-left:-10px;margin-top:-10px;border-radius:50%}.linedots div>span{white-space:nowrap;position:absolute}.linedots div.label-above>span,.linedots div.label-below>span{transform:translateX(-50%)}.linedots div.label-left>span,.linedots div.label-right>span{top:50%;transform:translateY(-50%)}.linedots div.label-above span{bottom:100%}.linedots div.label-below span{top:100%}.linedots div.label-right span{left:100%}.linedots div.label-left span{right:100%}.linedots div.hoverlabel:hover>span{opacity:1}._gridlines{grid-row:2;grid-column:2;-ms-grid-row:2;-ms-grid-column:2;display:flex;flex-direction:column}._gridlines span{flex:1}._x-axis{grid-row:3;grid-column:2;-ms-grid-row:3;-ms-grid-column:2;position:relative;display:flex}._x-axis span{flex:1}._x-axis-grouping{position:absolute;bottom:0;left:0;width:100%;display:flex}._x-axis-grouping span{position:relative}._x-axis-grouping span::before{position:absolute;top:0;left:3px;right:3px;border-top:1px solid}.legend.right,.legend.rightbottom{grid-row:2;grid-column:4;-ms-grid-row:2;-ms-grid-column:4}.legend.right.middle,.legend.rightbottom.middle{align-self:center}.legend.right.end,.legend.rightbottom.end{align-self:end}.legend.bottom{grid-row:4;grid-column:2;-ms-grid-row:4;-ms-grid-column:2}.legend.bottom.center{justify-self:center}.legend.bottom.end{justify-self:end}@media (max-width:767px){.legend.rightbottom{grid-row:4;grid-column:2;-ms-grid-row:4;-ms-grid-column:2}.legend.rightbottom.end,.legend.rightbottom.middle{align-self:inherit}}.legend span{float:left}.legend .symbol{width:1rem;height:1rem;float:left;margin-top:.5rem;margin-right:.5rem;position:relative}.legend .symbol.line:before{top:50%;transform:translateY(-50%);position:absolute;width:1rem;height:2px;background-color:currentColor}.legend:not(.rowbreak) .serie{display:inline-block}.legend:not(.rowbreak).bottom.start .serie{margin-right:1rem}.legend:not(.rowbreak).bottom.center .serie{margin-right:.5rem;margin-left:.5rem}.legend.rowbreak.right,.legend.rowbreak.rightbottom,.legend:not(.rowbreak).bottom.end .serie,.legend:not(.rowbreak).right,.legend:not(.rowbreak).rightbottom .serie{margin-left:1rem}.legend.rowbreak .serie{clear:both;overflow:auto}._pie ._chart-area>svg{pointer-events:initial}._pie ._pie-labels{pointer-events:none}._pie .hoverlabel{opacity:0}._pie:has(path.serie-0:hover) .hoverlabel.serie-0,._pie:has(path.serie-10:hover) .hoverlabel.serie-10,._pie:has(path.serie-11:hover) .hoverlabel.serie-11,._pie:has(path.serie-12:hover) .hoverlabel.serie-12,._pie:has(path.serie-13:hover) .hoverlabel.serie-13,._pie:has(path.serie-14:hover) .hoverlabel.serie-14,._pie:has(path.serie-15:hover) .hoverlabel.serie-15,._pie:has(path.serie-16:hover) .hoverlabel.serie-16,._pie:has(path.serie-17:hover) .hoverlabel.serie-17,._pie:has(path.serie-18:hover) .hoverlabel.serie-18,._pie:has(path.serie-19:hover) .hoverlabel.serie-19,._pie:has(path.serie-1:hover) .hoverlabel.serie-1,._pie:has(path.serie-20:hover) .hoverlabel.serie-20,._pie:has(path.serie-2:hover) .hoverlabel.serie-2,._pie:has(path.serie-3:hover) .hoverlabel.serie-3,._pie:has(path.serie-4:hover) .hoverlabel.serie-4,._pie:has(path.serie-5:hover) .hoverlabel.serie-5,._pie:has(path.serie-6:hover) .hoverlabel.serie-6,._pie:has(path.serie-7:hover) .hoverlabel.serie-7,._pie:has(path.serie-8:hover) .hoverlabel.serie-8,._pie:has(path.serie-9:hover) .hoverlabel.serie-9{opacity:1}._pie .legend.bottom{grid-column-start:1;grid-column-end:4;-ms-grid-column-start:1;-ms-grid-column-end:4}._pie-labels{z-index:1}._pie-labels div{position:absolute}._pie-label{white-space:nowrap;transform:translate(-50%,-50%)}._pie-connect:after{position:absolute;left:50%;width:1px;height:100%;background:#000}figure._chart._flippedbar ._y-axis{flex-direction:row-reverse;grid-row:3!important;-ms-grid-row:3!important;grid-column:2;-ms-grid-column:2}figure._chart._flippedbar ._y-axis.top{grid-column:3;-ms-grid-column:3}figure._chart._flippedbar ._y-axis.bottom{grid-column:1;-ms-grid-column:1}figure._chart._flippedbar ._y-axis span{transform:translateX(1rem)}figure._chart._flippedbar ._chart-area,figure._chart._flippedbar ._x-axis{margin:0}figure._chart._flippedbar ._x-axis{flex-direction:column;grid-row:2;grid-column:1}figure._chart._flippedbar ._x-axis span{display:flex;justify-content:flex-end;align-items:center;padding-right:.5rem}figure._chart._flippedbar ._gridlines{flex-direction:row;border-bottom:0;border-left:1px solid #000}figure._chart._flippedbar ._gridlines span{border-top:0;border-right:1px solid #ccc}figure._chart._flippedbar .bars.flippedbars{flex-direction:column;position:static;height:100%}figure._chart._flippedbar .bars.flippedbars div{position:relative;flex-direction:column}figure._chart._flippedbar .bars.flippedbars .bar{height:100%;position:absolute;top:50%;display:flex;flex-direction:row;align-items:center}figure._chart._flippedbar .bars.flippedbars .bar span{padding:0 1rem}figure._chart._flippedbar .bars.flippedbars .label-above .bar,figure._chart._flippedbar .bars.flippedbars .label-inside .bar{justify-content:flex-end}figure._chart._flippedbar .bars.flippedbars .label-above .bar span{transform:translateX(100%)}figure._chart._flippedbar .bars.flippedbars .label-center .bar{justify-content:center}figure._chart._flippedbar ._chart-area{max-height:none;min-height:0}figure._chart._flippedbar ._chart-area::after{padding-bottom:0}._chart-animation ._chartanimate .bar{transform-origin:0 100%;transform:scaleY(0)}._chart-animation ._chartanimate .bar.neg{transform-origin:0 0}._chart-animation ._chartanimate .bar._chart-animation-done{transform:none}._chart-animation .flippedbars ._chartanimate .bar{transform:scaleX(0)}._chart-animation .flippedbars ._chartanimate .bar._chart-animation-done{transform:none}._chart-animation ._chartanimate.stackedbar .bar{transform:scaleY(0) translateX(-50%)}._chart-animation ._chartanimate.stackedbar .bar._chart-animation-done{transform:scaleY(1) translateX(-50%)}@keyframes _linedots{0%{transform:scale(0)}40%{transform:scale(1.3)}to{transform:scale(1)}}._chart-animation .linedots ._chartanimate{opacity:0}._chart-animation .linedots ._chartanimate._chart-animation-done{opacity:1;animation-name:_linedots;animation-duration:.5s}._chart-animation-ready ._chartanimate .bar{transition:transform .6s}._chart-animation-ready ._linechart clipPath rect{transition:transform 1.5s linear}._chart-animation ._linechart clipPath rect{transform:scaleX(0)}._chart-animation ._linechart clipPath._chart-animation-done rect,body.logged-in.as-american-true #_main ._pagelist .item[data-opioid=true]:focus-visible,body.logged-in.as-american-true #_main ._pagelist 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auto}hr{color:#CCDBEB;background-color:#CCDBEB;border:none;height:1px;margin:2rem 0}._skiplink,h1{color:#232839}._block-content picture img,.parallax-mirror{border-radius:.375rem}@media (max-width:666px){hr{margin:1rem 0}}._skiplink{border:1px solid #232839}a,div,heading,ol,ul{box-sizing:border-box}body,button,input,select,textarea{font-family:Graphik,sans-serif;font-weight:400;font-size:1rem;line-height:1.75rem}.Heading1{font-size:3.8125rem;line-height:4.5625rem}.Heading2{font-size:2.75rem;line-height:3.125rem}.Heading3{font-size:2.125rem;line-height:2.75rem}.Heading4{font-size:1.75rem;line-height:2.5rem}#searchresults,._imagelist,._pagecontent,._pagelist,._pagelist-filter,._section-container ol,._section-container ul,._subscribe,.video-16-9,h1,h2,h3,h4,h5,h6,p,table{max-width:84.375rem;margin:0 auto}._block-content picture>img{display:block;max-width:min(84.375rem,100%);margin:0 auto}header 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2.5rem}.open-access-list{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));column-gap:1.5rem;row-gap:2rem;padding:0}style:first-child+.open-access-list{padding-top:3rem}.open-access-list.material-list{padding:0 0 2.5rem;border-bottom:1px solid rgba(0,0,0,.15)}.open-access-list .item{display:flex;flex-direction:column;padding:0 0 2rem}.open-access-list .item ._image{border-radius:.5rem;overflow:hidden;aspect-ratio:1.62055336}.open-access-list .item ._image img{width:100%;height:100%;object-fit:cover;object-position:center;scale:1.01;transition:scale .3s}.open-access-list .item h3{padding:1.375rem 0 .25rem;font-size:1.5rem;line-height:1.95rem;color:#3E4765;font-weight:600}.open-access-list .item p{padding:0;font-size:.875rem;line-height:1.25rem;text-transform:uppercase;font-weight:400;color:#4E515E}.open-access-list .item:focus-visible ._image picture img,.open-access-list .item:hover ._image picture img{scale:1.1}@media (max-width:1279px){.open-access-list .item h3{padding:.875rem 0 .125rem;font-size:1.25rem;line-height:1.625rem}}@media (max-width:1023px){.open-access-list{grid-template-columns:repeat(2,minmax(0,1fr));row-gap:1rem}}@media (max-width:599px){.open-access-list{grid-template-columns:1fr;row-gap:0}}@media (max-width:1250px){header,header ._container ._mainnav,header ._container ._searchform{box-shadow:0 7px 7px 0 rgba(0,0,0,.05)}header{z-index:10;background:#FFF;height:75px}header ._container{overflow:visible}header ._container ._ribbon{display:none}header ._container ._toggle-nav{margin:1.0625rem 0 1.0625rem 1.25rem;line-height:0;z-index:10}header ._container ._toggle-nav button#_toggle-nav{z-index:20;width:2.5625rem;height:2.5625rem;border-radius:.375rem;background:#CCDBEB}header ._container ._toggle-nav #_toggle-nav::after,header ._container ._toggle-nav #_toggle-nav>span::after,header ._container ._toggle-nav #_toggle-nav>span::before{width:1.5rem;background:#627EB3;height:2px;border-radius:1px;left:8.5px}header ._container ._toggle-nav button{margin:0}header ._container ._logo{padding:0 3.8125rem 0 0;width:22.3125rem;height:2.125rem}header ._container ._logo>a{background:0 0;padding:0}header ._container ._login,header ._container ._mainnav,header ._container ._searchform{background:#CCDBEB;padding:.5rem 1.5rem;width:calc(100% - 20px);max-width:37.5rem;box-sizing:border-box}header ._container ._mainnav{padding-top:6.25rem;margin:-4.6875rem 0 0;max-height:calc(100vh - 84px);min-height:75vh;height:auto;overflow-y:auto}header ._container ._mainnav>ul>li>a,header ._container ._mainnav>ul>li>span{font-size:1.125rem;line-height:1.375rem}header ._container ._mainnav li{display:block;margin:0 0 .5rem;position:relative}header ._container ._mainnav li ul{padding:0 0 0 1.5rem}header ._container ._mainnav li ul>li:first-child{padding:.5rem 0 0}header ._container ._mainnav li a,header ._container ._mainnav li span{color:#3E4765;padding:.25rem 0;width:fit-content;display:inline}header ._container ._mainnav li ._toggle{margin:auto 0 auto auto;background:0 0;position:absolute;right:0}header ._container ._mainnav li ._toggle svg{width:1.5rem}header ._container ._mainnav li ._toggle svg.hide{transform:rotate(90deg)}header ._container ._mainnav li._menuitem.selected>a{font-weight:500;background-size:0 1px,100% 1px}header ._container ._mainnav li._temporary-closed>a,header ._container ._mainnav li._temporary-closed>span,header ._container ._mainnav li.children-visible._temporary-closed>a,header ._container ._mainnav li.children-visible._temporary-closed>span,header ._container ._mainnav li.children-visible.expanded>a,header ._container ._mainnav li.children-visible.expanded>span,header ._container ._mainnav li.expanded>a,header ._container ._mainnav li.expanded>span{font-weight:500}header ._container ._login{z-index:2;position:absolute;top:1.0625rem;background:0 0;padding-top:0;padding-bottom:0;min-height:2.5625rem;display:flex;justify-content:flex-end;align-items:center}header ._container ._login #login,header ._container ._login #username{font-size:.938rem;line-height:1.281rem;margin:0;display:block;text-align:right}header ._container ._login #username{min-height:2.5625rem}header ._container ._login #user{width:fit-content;max-width:calc(100vw - 130px);margin:0 0 0 auto;height:2.5625rem;text-align:right}header ._container ._login #user .popup{width:fit-content;right:0}header ._container ._login button#login{color:#3E4765;background:0 0;padding:0 0 .375rem}header ._container ._login button#login svg{height:1.375rem;position:relative;top:.25rem;margin:0 .375rem 0 0;transform:translateY(1px)}header ._container ._login button#login span{display:inline;text-decoration:none;background-image:linear-gradient(transparent,transparent),linear-gradient(currentColor,currentColor);background-size:100% 1px,0 1px;background-position:100% 100%,0 100%;background-repeat:no-repeat;transition:all .3s,background .3s ease-out;padding-bottom:3px}header ._container ._login button#login span:hover{background-size:0 1px,100% 1px}header ._container ._login button#login:focus-visible svg #shackle,header ._container ._login button#login:hover svg #shackle{transform:rotateZ(30deg);transition:transform .3s .3s}header ._container ._searchform{border-radius:0 0 1.5625rem;padding-bottom:2rem;z-index:3;grid-column-end:-1}header ._container ._searchform form._placeholder{height:2.75rem!important;position:static!important;display:flex;align-items:center;column-gap:.5rem}header ._container ._searchform form._placeholder input._searchfield{position:static;opacity:1;display:block!important;background:#FFF;width:100%!important;flex:1;padding:.5rem 1rem;font-size:1rem!important;line-height:1.75rem!important;color:#232839;outline:0;border:none;box-sizing:border-box;border-radius:.375rem;cursor:text}header ._container ._searchform form._placeholder input._searchfield::placeholder{color:#232839}header ._container ._searchform form._placeholder ._searchsubmit{display:block;margin:0;width:2.75rem;height:2.75rem;background-image:url(data:image/svg+xml,%3C?xml%20version%3D%221.0%22%20?%3E%3Csvg%20width%3D%2216%22%20height%3D%2217%22%20viewBox%3D%220%200%2016%2017%22%20fill%3D%22none%22%20xmlns%3D%22http%3A//www.w3.org/2000/svg%22%3E%3Cpath%20d%3D%22M7.66634%2014.5016C11.1641%2014.5016%2013.9997%2011.6661%2013.9997%208.16829C13.9997%204.67049%2011.1641%201.83496%207.66634%201.83496C4.16854%201.83496%201.33301%204.67049%201.33301%208.16829C1.33301%2011.6661%204.16854%2014.5016%207.66634%2014.5016Z%22%20stroke%3D%22%23FFFFFF%22%20stroke-width%3D%221.5%22%20stroke-linecap%3D%22round%22%20stroke-linejoin%3D%22round%22/%3E%3Cpath%20d%3D%22M14.6663%2015.1683L13.333%2013.835%22%20stroke%3D%22%23FFFFFF%22%20stroke-width%3D%221.5%22%20stroke-linecap%3D%22round%22%20stroke-linejoin%3D%22round%22/%3E%3C/svg%3E);background-repeat:no-repeat;background-position:center;background-size:24px 24px;font-size:0;line-height:0}header ._container 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40px);max-width:18.5rem;height:auto}}@media (max-width:1250px) and (max-width:599px){header ._container ._mainnav{padding-top:5rem}}@media (min-width:1251px){html[lang=en] header ._searchform{width:4.5rem}html[lang=en] header ._searchform:after{content:'Search'}html[lang=en] header ._searchform form>._searchfield{min-width:4.5rem}html[lang=sv] header ._searchform{width:3.125rem}html[lang=sv] header ._searchform:after{content:'Sök'}html[lang=sv] header ._searchform form>._searchfield{min-width:3.125rem}header{padding:0}header ._container{padding:0 1rem}header ._container ._searchform,header ._container .lang-picker,header ._container .site-selector{font-size:.938rem;line-height:1.5rem;height:3.125rem;padding:.75rem 0}header ._container ._searchform div>button,header ._container .lang-picker div>button,header ._container .site-selector div>button{font-size:.938rem;line-height:1.5rem;display:flex;align-items:center;transition:background .3s,color .3s}header ._container ._searchform{display:flex;align-items:center}header ._container ._searchform:after{display:inline;margin:0 0 0 .4375rem;transition:color .3s}header ._container ._searchform ._searchicon{width:1rem;min-width:1rem;height:1rem;margin:2px 0 0;transition:color .3s}header ._container ._searchform ._placeholder{margin-top:1px;overflow:hidden;box-shadow:0 7px 7px 0 rgba(0,0,0,.05)}header ._container ._logo{box-sizing:border-box;height:3.5625rem;display:flex;align-items:center;min-width:20.875rem;transition:border .3s}header ._container ._logo>a{min-width:20.875rem;padding:0 2.5rem 0 0;background:0 0}header ._container ._logo>a svg{height:2.125rem;width:18.5rem;transition:color .3s}header ._container ._login{margin-right:1.375rem}header ._container ._login #login{font-size:.938rem;line-height:1.5rem;color:#3E4765;display:flex;align-items:center;gap:.5625rem;background:0 0;padding:0;margin:0}header ._container ._login #login:focus-visible svg #shackle,header ._container ._login #login:hover svg #shackle{transform:rotateZ(30deg);transition:transform .3s .3s}header ._container ._mainnav{box-sizing:border-box;height:3.5625rem;transition:border .3s;max-width:84.375rem;margin:0 auto}header ._container ._mainnav li{display:flex;flex-wrap:wrap}header ._container ._mainnav .level1{flex:1}header ._container ._mainnav .level1>li{margin-bottom:-.125rem;transition:border .3s,color .3s;border-bottom:1px solid transparent}header ._container ._mainnav .level1>li>a,header ._container ._mainnav .level1>li>span{font-size:1.063rem;line-height:1.5rem;padding:.1875rem .25rem .3125rem;color:#3E4765;align-items:center;display:flex;position:relative}header ._container ._mainnav .level1>li:not(:last-child){margin-right:1.3125rem}header ._container ._mainnav .level1>li:last-child a{padding-right:0}header ._container ._mainnav .level2,header ._container ._mainnav .level3{display:none!important}header ._container ._ribbon{width:100%;transition:all .3s}header ._container ._ribbon ul{max-width:86.375rem;margin:0 auto;align-items:center;column-gap:1.25rem;row-gap:.75rem;padding:.9375rem 1rem;flex-wrap:wrap;transition:height .3s;position:relative}header ._container ._ribbon ul li:not(._ribbonToggle){display:flex;align-items:center;padding:0 .25rem .125rem;position:relative}header ._container ._ribbon ul li:not(._ribbonToggle) a{padding:0;margin:0;white-space:nowrap}header ._container ._ribbon ul a{font-size:1.063rem;line-height:1.5rem;color:#3E4765}header ._container ._ribbon ul ._ribbonParent a{font-weight:500;display:flex;align-items:center}header ._container ._ribbon ul ._ribbonParent a:after{content:'';display:block;width:.25rem;min-width:.25rem;height:.5rem;margin:0 0 0 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._container ._ribbon ul:not(:has(li.selected)) ._ribbonParent:not(._ribbonBack)>a{text-decoration:underline;text-underline-offset:.4375rem;background:0 0!important}._container ._mainnav .level1>li.selected>a,header ._container ._ribbon ul .selected>a{background-size:0 1px,100% 1px;color:#315496;background-image:linear-gradient(transparent,transparent),linear-gradient(#627EB3,#627EB3)}header ._container ._ribbon ul .selected>a{font-weight:500}header ._container ._ribbon ul ._ribbonToggle{display:none}._container ._mainnav .level1>li.expanded>a,._container ._mainnav .level1>li.selected>a{font-weight:500;color:#315496}body header,body header ._ribbon ul a,body header ._searchform:after,body header .lang-picker .dropdown button,body header .site-selector .dropdown button{color:#3E4765}body.no-ribbon header ._container ul.level1>li>a{margin-bottom:-1px}body._level0 header ._container,body.no-ribbon header ._container,body:not(.level_0) header ._ribbon{box-shadow:0 7px 7px 0 rgba(0,0,0,.05)}body.no-ribbon header ._container ._mainnav{border-bottom:none}body:not(._level0) header ._mainnav{border-bottom:1px solid rgba(0,0,0,.12)}body header{background:#FFF}body header ._mainnav{border-top:1px solid rgba(0,0,0,.12)}body header ._mainnav .level1>li.has-children>a:after{background-image:url("data:image/svg+xml,%3Csvg width='7' height='4' fill='none' xmlns='http://www.w3.org/2000/svg'%3E%3Cpath d='M.854.146a.5.5 0 1 0-.708.708l3 3a.502.502 0 0 0 .708 0l3-3a.5.5 0 1 0-.708-.708L3.5 2.793.854.146Z' fill='%233E4765'/%3E%3C/svg%3E")}body header ._ribbon{background:#FFF}header{transition:all .5s ease-in-out}header:focus-visible,header:hover{transition-delay:.8s;top:0!important;transform:none!important}body:not(._level0) header{top:0}body._level0 header{top:0;transform:none!important}body._level0 header.headroom--not-top:not(.headroom--pinned){top:-3.625rem}body:not(._level0).no-ribbon header.headroom--unpinned{top:3.5rem}body.no-ribbon ._ribbon{display:none}body.no-ribbon header ._container ._mainnav .level1>li._menuitem{margin-bottom:-.0625rem}body.ribbon ._searchform.focus-within ._placeholder{top:10.125rem}body.ribbon.double-ribbon ._searchform.focus-within ._placeholder{top:12.375rem}body.ribbon.triple-ribbon ._searchform.focus-within ._placeholder{top:14.625rem}body #_main{margin-top:7.125rem}body.no-ribbon main ._section-container:first-of-type{margin-top:0}body.ribbon main ._section-container:first-of-type{margin-top:3.5rem}}@media (min-width:1251px) and (min-width:1251px) and (max-width:1299px){header ._container ._logo a{padding:0 1.5rem 0 0}}._pagelist:not(.open-access-list){display:grid;grid-template-columns:repeat(3,minmax(0,1fr));column-gap:1.5rem;row-gap:4rem;padding:2.5rem 0 0}._pagelist:not(.open-access-list):not(.upcoming,.publication){padding:3.75rem 0 2.5rem;margin:2.5rem 0 0;border-top:1px solid rgba(0,0,0,.15)}._pagelist:not(.open-access-list).upcoming{padding:1.8125rem 0 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.serie-1.bar:not(.label-above) span,._chart .serie-1:not(.label-above) .bar span{color:#fff}._chart .combinedlabel .serie-1 ._lbl::before,._chart .legend .serie-1,._chart .serie-1 .bar,._chart .stackedbar .serie-1{background-color:#c8d2d4}._chart .serie-1 line{stroke:#c8d2d4}._chart .serie-1 svg{color:#c8d2d4}._chart path.serie-1,._chart polygon.serie-1{fill:#c8d2d4}._chart .legend .line.serie-1{background-color:transparent;color:#c8d2d4}._chart ._pie-label.serie-1:not(.outside),._chart .serie-2.bar:not(.label-above) span,._chart .serie-2:not(.label-above) .bar span{color:#fff}._chart .combinedlabel .serie-2 ._lbl::before,._chart .legend .serie-2,._chart .serie-2 .bar,._chart .stackedbar .serie-2{background-color:#7cc8c5}._chart .serie-2 line{stroke:#7cc8c5}._chart .serie-2 svg{color:#7cc8c5}._chart path.serie-2,._chart polygon.serie-2{fill:#7cc8c5}._chart .legend .line.serie-2{background-color:transparent;color:#7cc8c5}._chart ._pie-label.serie-2:not(.outside),._chart .serie-3.bar:not(.label-above) span,._chart .serie-3:not(.label-above) .bar span{color:#fff}._chart .combinedlabel .serie-3 ._lbl::before,._chart .legend .serie-3,._chart .serie-3 .bar,._chart .stackedbar .serie-3{background-color:#627eb3}._chart .serie-3 line{stroke:#627eb3}._chart .serie-3 svg{color:#627eb3}._chart path.serie-3,._chart polygon.serie-3{fill:#627eb3}._chart .legend .line.serie-3{background-color:transparent;color:#627eb3}._chart ._pie-label.serie-3:not(.outside),._chart .serie-4.bar:not(.label-above) span,._chart .serie-4:not(.label-above) .bar span{color:#fff}._chart .combinedlabel .serie-4 ._lbl::before,._chart .legend .serie-4,._chart .serie-4 .bar,._chart .stackedbar .serie-4{background-color:#a286ae}._chart .serie-4 line{stroke:#a286ae}._chart .serie-4 svg{color:#a286ae}._chart path.serie-4,._chart polygon.serie-4{fill:#a286ae}._chart .legend .line.serie-4{background-color:transparent;color:#a286ae}._chart ._pie-label.serie-4:not(.outside),._chart .serie-5.bar:not(.label-above) span,._chart .serie-5:not(.label-above) .bar span{color:#fff}._chart .combinedlabel .serie-5 ._lbl::before,._chart .legend .serie-5,._chart .serie-5 .bar,._chart .stackedbar .serie-5{background-color:#f18979}._chart .serie-5 line{stroke:#f18979}._chart .serie-5 svg{color:#f18979}._chart path.serie-5,._chart polygon.serie-5{fill:#f18979}._chart .legend .line.serie-5{background-color:transparent;color:#f18979}._chart ._pie-label.serie-5:not(.outside),._chart .serie-6.bar:not(.label-above) span,._chart .serie-6:not(.label-above) .bar span{color:#fff}._chart .combinedlabel .serie-6 ._lbl::before,._chart .legend .serie-6,._chart .serie-6 .bar,._chart .stackedbar .serie-6{background-color:#a2bfde}._chart .serie-6 line{stroke:#a2bfde}._chart .serie-6 svg{color:#a2bfde}._chart path.serie-6,._chart polygon.serie-6{fill:#a2bfde}._chart .legend .line.serie-6{background-color:transparent;color:#a2bfde}._chart ._pie-label.serie-6:not(.outside),._chart .serie-7.bar:not(.label-above) span,._chart .serie-7:not(.label-above) .bar span{color:#fff}._chart .combinedlabel .serie-7 ._lbl::before,._chart .legend .serie-7,._chart .serie-7 .bar,._chart .stackedbar .serie-7{background-color:#cddbec}._chart .serie-7 line{stroke:#cddbec}._chart .serie-7 svg{color:#cddbec}._chart path.serie-7,._chart polygon.serie-7{fill:#cddbec}._chart .legend .line.serie-7{background-color:transparent;color:#cddbec}._chart ._pie-label.serie-7:not(.outside){color:#fff}tr.serie-0 button{background-color:#3e4765;color:#fff}tr.serie-1 button{background-color:#c8d2d4;color:#fff}tr.serie-2 button{background-color:#7cc8c5;color:#fff}tr.serie-3 button{background-color:#627eb3;color:#fff}tr.serie-4 button{background-color:#a286ae;color:#fff}tr.serie-5 button{background-color:#f18979;color:#fff}tr.serie-6 button{background-color:#a2bfde;color:#fff}tr.serie-7 button{background-color:#cddbec;color:#fff}body.live.js ._animation{animation-duration:1s;animation-fill-mode:both}body.live.js ._animation:not(._animated){opacity:0}